IP-10 Antilichaam

Interferon-gamma-inducible 10 kD protein (IP-10), is a CXC chemokine with chemoattractant properties for CD4-positive T cells and inhibits early normal and leukemic hemopoietic progenitor proliferation. IP-10 is produced by a wide variety of cell types ranging from neutrophils and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV encephalitis, cutaneous T cell lymphoma, chronic hepatitis and acute anterior uveitis. Various observations strongly suggest a role for the CXC chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis.

15945

P17515

P17515

Mouse

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant mIP-10 (murine IP-10) .

Unconjugated

Primary Antibodies, Functional Antibodies, Antibody Pairs

Chemokines & Cytokines

Anti-mIP-10 specific antibody was purified by affinity chromatography employing immobilized mIP-10 matrix.

Batch dependent

None

Room Temp

IP-10 antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

Cxcl10

Chemokine (C-X-C motif) ligand 10

Mus musculus

C7, IP10, CRG-2, INP10, IP-10, Ifi10, mob-1, Scyb10, gIP-10, Crg2, Inp10, C-X-C motif chemokine 10, 10 kDa interferon gamma-induced protein, Gamma-IP10

ELISA, WB, Neutralization Assay

124494

Lyophilized