IP-10 (CXCL10)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant human IP-10 is an 8.6 kDa protein consisting of 77 amino acids including the four conserved cysteine residues present in CXC chemokines.
CXCL10
3627
P02778
NP_001556.2
NM_001565.3
4q21
Human
Monkey, Mouse, Leech, Human
VPLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFCPRVEIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP
< 0.1 ng/µg of protein (< 1EU/µg)
> 98% by SDS-PAGE & HPLC analyses
Determined by its ability to chemoattract human T-Lymphocytes using a concentration of 10-50 ng/ml.
77
Lyophilized
8.6 kDa
E. coli
Beschrijving
IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulate
Specificaties
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