IP-10 (CXCL10)
Gecertificeerd

IP-10 (CXCL10)

Catalog #: R20-075-L500
Maat: 500 µg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

Description

IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant rat IP-10 is an 8.6 kDa protein consisting of 77 amino acids including the four conserved cysteine residues present in CXC chemokines.

Synonyms

Gamma-Interferon inducible protein 10, CXCL10, crg-2

NCBI Gene ID

245920

UniProt

P48973

Accession Number

NP_620789.1

Accession Number mRNA

NM_139089.1

Chromosomal Location

14p22

Reactivity

Rat

Cross Reactivity

Rat, Human

Sequence

IPLARTVRCT CIDFHEQPLR PRAIGKLEII PASLSCPHVE IIATMKKNNE KRCLNPESEA IKSLLKAVSQ RRSKRAP

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

> 98% by SDS-PAGE & HPLC analyses

Bioactivity

Determined by its ability to chemoattract hCXCR3/HEK293 cells using a concentration range of 10.0-50.0 ng/ml.

Length

77

Form

Lyophilized

Molecular Weight

8.6 kDa

Host or Source

E. coli

Beschrijving

IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulate

Specificaties

ProductnaamIP-10 (CXCL10)
Categorie
Beschikbare grootte500 µg
CatalogusnummerR20-075-L500