IPH5201
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
IPH5201 is a human IgG1 monoclonal antibody (mAb) targeting ENTPD1/CD39. IPH5201 accumulates immunostimulatory ATP released by tumor cells treated with combination chemotherapy (CT) and reduces immunosuppressive Ado levels in the tumor microenvironment (TME). IPH5201 can be used in anti-tumor immunity research. Recommended isotype control: Human IgG1 kappa, Isotype Control.
12352203
NTPDase
Immunology/Inflammation
Cancer-programmed cell death
Cancer
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[1]Barlesi F, et al. 1290TiP A phase II multicenter, open label, non-randomized study of neoadjuvant and adjuvant treatment with IPH5201 and durvalumab in patients with resectable, early-stage (II to IIIA) non-small cell lung cancer (MATISSE) [J]. Annals of Oncology, 2023, 34: S744.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991444/
Inhibitory Antibodies
No Development Reported
Beschrijving
IPH5201 is a human IgG1 monoclonal antibody (mAb) targeting ENTPD1/CD39. IPH5201 accumulates immunostimulatory ATP released by tumor cells treated with combinat
Specificaties
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