IPO8 Antilichaam

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

10526

O15397

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 878-1037 of human IPO8 (NP_006381.2) .

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 120kDa

IgG

WB: 1:500 - 1:2000

IPO8

Jurkat

Mouse brain

Rat testis

Importin 8

Homo sapiens

IPO8, importin 8, RANBP8, RAN-binding protein 8

WB

Liquid