IPrAgCl

IPrAgCl is an antibacterial agent. IPrAgCl exhibits antiproliferative activity against MCF7 cell line with an IC50 of 30 nM. IPrAgCl has an IC50 of 35 nM against KB cancer cell line. IPrAgCl induces apoptosis in HL60 cell line. IPrAgCl promotes apoptosis-inducing factor translocation from the mitochondrial to the nuclear compartment[1].

873297-19-9

12352005

H302, H315, H319, H335

Bacterial

Anti-infection

Cancer; Infection

97.0

Cl[Ag]=C1N(C=CN1C=2C(=CC=CC2C(C)C)C(C)C)C=3C(=CC=CC3C(C)C)C(C)C

C27H36AgClN2

531.92

H302, H315, H319, H335

[1]Eloy L, et al., Anticancer activity of silver-N-heterocyclic carbene complexes: caspase-independent induction of apoptosis via mitochondrial apoptosis-inducing factor (AIF) . ChemMedChem. 2012 May;7 (5) :805-14.

Room Temperature

4°C (Powder, protect from light, stored under nitrogen)

http://file.medchemexpress.com/batch_PDF/HY-W047131/

Reference compound2

No Development Reported