IRAK1 (fosfo Ser376) Antilichaam

IRAK1 encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.

3654

P51617

NP_001560.2

Human

IRAK1 (phospho Ser376) antibody was raised against a peptide sequence around phosphorylation site of Serine 376 (Q-S-S (p) -M-V) derived from Human IRAK1.

Unconjugated

Primary Antibodies

Phospho-Specific , Inflammasomes

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

76 kDa

IgG

The antibody detects endogenous levels of IRAK1 only when phosphorylated at serine 376.

IRAK1

Interleukin-1 receptor-associated kinase 1

Homo sapiens

Cao Z., Science 271:1128-1131 (1996) .

Reichwald K., Mamm. Genome 11:182-190 (2000) .

Jensen L.E., J. Biol. Chem. 276:29037-29044 (2001) .

IL1RAK, IRAK, mPLK

IHC

8928535

Liquid