IRAK4 Adenovirus (Ad-IRAK4)
Gecertificeerd

IRAK4 Adenovirus (Ad-IRAK4)

Catalog #: 1578
Maat: 200 µL
Droogijs Vereist

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

Description

Interleukin-1 receptor (IL1R) -associated kinases (IRAKs) are important mediators in the signal transduction of Toll-like receptor (TLR) and IL-1R family members, collectively referred to as TIRs. Binding of IL-1 to its cognate receptor results in the activation of the NFkB signaling pathway. 100 kDa IRAK-1 is implicated as an upstream mediator of NFkB activation. IRAK-2 is a proximal mediator of IL-1, a component of the IL-1R signaling complex and is required for IL-1R-induced NFkB activation. IRAK-4 is strongly expressed in kidney and is also found in lung, testis, small intestine, breast, liver, and placenta. In contrast to the other IRAKs that are expressed in most cell types, IRAK-M is restricted to monocytic cells.

Product Name Alternative

IRAK4 Adenovirus

UNSPSC

41106621

HS Code

3822190000

Type

Pre-Made

Shipping Conditions

Dry Ice

Storage Conditions

-80C

Shelf Life

12 Months

Short Name

Ad-IRAK4

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV (ubiquitous)

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Ttiter

1x10^10 PFU/ml

Beschrijving

Interleukin-1 receptor (IL1R) -associated kinases (IRAKs) are important mediators in the signal transduction of Toll-like receptor (TLR) and IL-1R family member

Specificaties

ProductnaamIRAK4 Adenovirus (Ad-IRAK4)
Categorie
Beschikbare grootte200 µL
Catalogusnummer1578