IRF1 Antilichaam - N-terminaal gebied: Biotine (ARP31296_P050-Biotine)

Interferon regulatory factor 1

MAR, IRF-1

3659

P10914

NP_002189

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

The immunogen is a synthetic peptide directed towards the N terminal region of human IRF1

IRF1 is interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

SUMO2; SUMO3; IRF2; KAT2B; EP300; PRDM1; UBC; BIRC3; MDM2; HIST1H3A; CBL; HSP90AA1; HSPA1A; Tbk1; STUB1; SPI1; QARS; IRF8; CDKN1B; TRIM28; SET; SP2; IRF9; YBX1; NPM1; TRMT2A; HCFC1; SEC63; KEAP1; TRAF3; CREBBP; tat; SMARCA4; STAT1; HMGA1; RELA; NFKB1; KAT

Biotin

Polyclonal Antibody

WB, IHC

Affinity Purified

0.5 mg/ml

Cow: 85%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 85%; Rabbit: 86%; Rat: 92%; Sheep: 85%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

36kDa

Kamitani, S., (2008) Biochem. Biophys. Res. Commun. 370 (2), 366-370

Wet Ice

325

IRF1

IRF1

Rabbit

Interferon regulatory factor 1

NM_002198

RMLPPLTKNQRKERKSKSSRDAKSKAKRKSCGDSSPDTFSDGLSSSTLPD