IRF1 Antilichaam - N-terminaal gebied: Biotine (ARP38128 P050-Biotine)

Interferon regulatory factor 1

MAR, IRF-1

3659

P10914

NP_002189

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human IRF1

IRF1 is interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppression.

SUMO2; SUMO3; IRF2; KAT2B; EP300; PRDM1; UBC; BIRC3; MDM2; HIST1H3A; CBL; HSP90AA1; HSPA1A; Tbk1; STUB1; SPI1; QARS; IRF8; CDKN1B; TRIM28; SET; SP2; IRF9; YBX1; NPM1; TRMT2A; HCFC1; SEC63; KEAP1; TRAF3; CREBBP; tat; SMARCA4; STAT1; HMGA1; RELA; NFKB1; KAT

Biotin

Polyclonal Antibody

WB, IHC

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 92%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

37kDa

Kumar, A., (2005) J. Biol. Chem. 280 (52), 42619-42626

Wet Ice

325

IRF1

IRF1

Rabbit

Interferon regulatory factor 1

NM_002198

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