IRF3 Antilichaam, ko gevalideerd

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

3661

Q14653

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human IRF3 (NP_001184051.1) .

Unconjugated

Primary Antibodies

Antibody is Knockout validated.

Chemokines & Cytokines, Immunology, Innate Immunity, Transcription, Inflammasomes

Affinity purification

293T

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 56kDa

IgG

IRF3

HeLa

Jurkat

HepG2

Interferon regulatory factor 3

Homo sapiens

IRF3 Antibody: Interferon regulatory factor 3, IRF-3

WB, IHC, ChIP

Liquid