IRF4 Antilichaam - middengebied HRP (ARP38155_P050-HRP)

Interferon regulatory factor 4

MUM1, LSIRF, SHEP8, NF-EM5

3662

Q15306

NP_002451

Human, Rat, Dog, Guinea Pig, Horse

The immunogen is a synthetic peptide directed towards the middle region of human IRF4

IRF4 is a transcriptional activator. It binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter.It also binds the immunoglobulin lambda light chain enhancer, together with PU.1. IRF4 probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells.

UBC; STAT6; BCL6; TOP1; IRAK1; PRRC2B; YTHDC2; VPS35; PEG10; TLK2; CARM1; IKBKAP; ETV7; BATF; HOXB13; PROX1; HOXC11; FKBP4; SPIB; PRDM1; MYD88; TRAF2; NFATC2; SPI1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

IRF4 is strongly supported by BioGPS gene expression data to be expressed in 721_B

0.5 mg/ml

Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Rat: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

52kDa

Han, J., (er) PLoS Genet. 4 (5), E1000074 (2008)

Wet Ice

451

IRF4

IRF4

Rabbit

Interferon regulatory factor 4

NM_002460

TAHVEPLLARQLYYFAQQNSGHFLRGYDLPEHISNPEDYHRSIRHSSIQE