IS4
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
3067986-23-3
CXCR
GPCR/G Protein, Immunology/Inflammation, Autophagy
IS4 is a selective competitive antagonist of CXCR4, exhibiting an IC50 of 0.65 nM in THP-1 cells and 38.75 nM in Jurkat cells. It remains stable in serum and is non-cytotoxic. IS4 competes with CXCL12 for binding to CXCR4, thereby inhibiting CXCL12-induced intracellular Ca2+ release and cancer cell migration. This compound is applicable in research on the prevention of metastasis in conditions such as breast cancer, prostate cancer, and leukemia.
O=C1C2=C(C(=O)N1CC#C)SC[C@@H](C(O)=O)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC([C@@H](NC([C@H](CCCNC(=N)N)NC(C)=O)=O)C)=O)CS2
C48H62N14O11S2
1075.22
Ice Packs
-20°C
Beschrijving
IS4 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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