Isethionzuur (80% in water) (standaard)

Isethionic acid (80% in water) (Standard) is the analytical standard of Isethionic acid (80% in water). This product is intended for research and analytical applications. Isethionic acid is a calcium binder and anionic detergent that enhances mitochondrial calcium binding capacity by competitively binding to calcium binding sites on the outer mitochondrial membrane. Isethionic acid can inhibit calcium-activated mitochondrial respiration. Isethionic acid inhibits barnacle (Balanus amphitrite) larvae with LC50s of 23 μg/mL (24 h) and 17 μg/mL (48 h), respectively. Isethionic acid can inhibit the attachment of barnacle larvae (complete inhibition at 10 μg/mL) and regulate mitochondrial calcium transport, and can enhance ATP-dependent calcium uptake at high calcium concentrations. Isethionic acid can be used to study the mechanism of mitochondrial calcium metabolism.

107-36-8

Mitochondrial Metabolism; Parasite; Reference Standards

Anti-infection; Metabolic Enzyme/Protease; Others

Metabolic Disease

O=S(CCO)(O)=O

C2H6O4S

126.13

[1]Hellio C, et al. Isethionic acid and floridoside isolated from the red alga, Grateloupia turuturu, inhibit settlement of Balanus amphitrite cyprid larvae. Biofouling. 2004 Jun;20 (3) :139-45.|[2]Dolara P, et al. Effect of 2-aminoethanesulphinic acid (taurine) and 2-hydroxyethane sulphonic acid (isethionic acid) on calcium transport by rat liver mitochondria. Biochem Pharmacol. 1973 Sep 1;22 (17) :2085-94.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-Y0095R/

Reference Standards