ISLR2 Polyklonale Antilichaam, AbBy FluorTM 488 Vervoeging

The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å / horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. ISLR2 (immunoglobulin superfamily containing leucine-rich repeat 2), also known as LINX (leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein), is a 745 amino acid single-pass membrane protein that contains five LRR repeats, one Ig-like (immunoglobulin-like) domain, a LRRCT domain and one LRRNT domain. ISLR2 exists as a homomultimer and is essential for axon extension during neural development. The gene encoding ISLR2 maps to human chromosome 15q24.1.

Immunoglobulin superfamily containing leucine-rich repeat protein 2; Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein; ISLR2_HUMAN.

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Extracellular

Human, Mouse, Rat

531-630/745

ISLR2

AbBy Fluor™ 488

KLH conjugated synthetic peptide derived from human ISLR2

WB, IF

Purified by Protein A.

499nm/519nm

1µg/µl

WB (WB=1:500-2000), IF (IF=1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

57611