ITGB1 (fosfo Tyr795) Antilichaam

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

3688

P05556

NP_002202.2

Human, Mouse, Rat

ITGB1 (phospho Tyr795) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 795 (P-K-Y (p) -E-G) derived from Human ITGB1 .

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

140 kDa

IgG

The antibody detects endogenous levels of ITGB1 only when phosphorylated at tyrosine 795.

Western Blot: 1:500~1:1000

ITGB1

Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)

Homo sapiens

Argraves W.S., J. Cell Biol. 105:1183-1190 (1987) .

Ota T., Nat. Genet. 36:40-45 (2004) .

Bechtel S., BMC Genomics 8:399-399 (2007) .

CD29, FNRB, ITB1

WB

19743813

Liquid