ITGB3BP Antibody - N-terminal regio : FITC (ARP55000_P050-FITC)

Integrin beta 3 binding protein (beta3-endonexin)

CENPR, NRIF3, TAP20, CENP-R, HSU37139

23421

Q13352-5

NP_055103

Human, Dog

The immunogen is a synthetic peptide directed towards the N-terminal region of Human ITGB3BP

This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.

PIH1D2; UBR7; ARFIP2; COL4A3BP; KIFC3; KDM1A; UBC; APP; CENPP; CENPO; SVIL; MAPK6; ACTN2; MTA1; ITGB3BP; DDX24; RECQL5; RXRA; ITGB3; NFKB1; ITGB5; ESR1; CCNA2; THRA; RELA; RXRG

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Dog: 91%; Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

23kDa

Wet Ice

216

ITGB3BP

ITGB3BP

Rabbit

Centromere protein R

QMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMML