ITGB3BP Mouse Monoclonal Antibody [Kloon ID: LBI4H1]

This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

Carrier-free (BSA/glycerol-free) ITGB3BP mouse monoclonal antibody, clone LBI4H1

CENP-R; CENPR; HSU37139; NRIF3; TAP20

Homo sapiens integrin subunit beta 3 binding protein (ITGB3BP), transcript variant 2, mRNA.

23421

Q13352

Unconjugated

WB 1:2000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Stem cell - Pluripotency, Transcription Factors

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

ITGB3BP

https://www.ncbi.nlm.nih.gov/gene/?term=23421

https://www.uniprot.org/uniprot/Q13352