Itraconazool
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Itraconazole inhibits the conversion of lanosterol to ergosterol via inhibition of the 14-α demethylase, a cytochrome P-450 enzyme1. Clinically useful antifungal agent. It inhibits the proliferation of glioblastoma cells in vitro and in vivo by inducing autophagic progression via inhibiting the trafficking of cholesterol from late endosomes and lysosomes to the plasma membrane2. Inhibits the hedgehog pathway by binding to Smoothened (SMO) via a mechanism distinct from that of cyclopamine3. Inhibits angiogenesis via inhibiting the binding of VEGF to VEGFR24.
Unconjugated
White solid
-20°C
Beschrijving
Itraconazool Beschikbaar in 50 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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