Ixazomib-citraat (MLN9708) Analoge
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1201902-80-8
C16685-10mg
Proteasome
Proteases
B1 (OC (=O) CC (O1) (CC (=O) O) C (=O) O) C (CC (C) C) NC (=O) CNC (=O) C2=C (C=CC (=C2) Cl) Cl
C20H23BCl2N2O9
Ixazomib Citrate (MLN9708) Analogue is the analogue of Ixazomib Citrate (MLN9708) from WO2016165677A1. Ixazomib Citrate (MLN9708) immediately hydrolyzed to Ixazomib (MLN2238), the biologically active form, on exposure to aqueous solutions or plasma. Ixazomib (MLN2238) inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50/Ki of 3.4 nM/0.93 nM in cell-free assays, less potent to β1 and little activity to β2. Ixazomib (MLN2238) induces autophagy. Phase 3.
2 years -80 in solvent
Beschrijving
Ixazomib-citraat (MLN9708) Analoge Beschikbaar in 10 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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