JADE2 Antilichaam / PHF15

PHF15, also known as Protein Jade-2, has 3 isoforms, a 790 amino acid isoform that is 87 kDa, a 789 amino acid isoform that is 87 kDa and a 562 amino acid isoform that is 63 kDa, has a histone H4-specific acetyltransferase activity as a component of the HBO1complex, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. This protein has been shown an interaction with ING4, KAT7, ING5, PACSIN, ZBTB3, ZBTB5, ZNF496, and VHL proteins in histone H3 acetylation, histone H4-K5 acetylation, histone H4-K8 acetylation, and histone H4-K12 acetylation biological processes.

Western blot: 0.5-1 µg/mL, ELISA: 0.1-0.5 µg/mL

Q9NQC1

Human

An E.coli-derived human recombinant protein (amino acids L397-D746) was used as the immunogen for the JADE2 antibody.

WB, ELISA

Antigen affinity purified

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This JADE2 antibody is available for research use only.

After reconstitution, the JADE2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the JADE2 antibody should be determined by the researcher.

Western blot testing of human 1) A431, 2) A549 and 3) SiHa cell lysate with JADE2 antibody. Predicted molecular weight ~87 kDa.