JAG2 Antilichaam / Jagged 2

Protein jagged-2, also known as SER2, is a protein that in humans is encoded by the JAG2 gene. It is mapped to 14q32.33. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Notch ligands Delta1 and JAG2 are subject to presenilin-dependent, intramembranous gamma-secretase processing, resulting in the production of soluble intracellular derivatives. JAG2 can promote the growth and dissemination of uveal melanoma cells.

Western blot: 1-2 µg/mL, ELISA: 0.1-0.5 µg/mL

Q9Y219

Human

An E.coli-derived human recombinant protein (amino acids Q22-N1153) was used as the immunogen for the JAG2 antibody.

WB, ELISA

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This JAG2 antibody is available for research use only.

After reconstitution, the JAG2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the JAG2 antibody should be determined by the researcher.

Western blot testing of human HeLa cell lysate with JAG2 antibody. Predicted molecular weight ~133 kDa, may be observed at higher molecular weights due to glycosylation.