JAK3 Mouse Monoclonal Antibody [Kloon ID: LBI2B4]

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease) . [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) JAK3 mouse monoclonal antibody, clone LBI2B4

JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK

Homo sapiens Janus kinase 3 (JAK3), mRNA.

3718

P52333

Unconjugated

Chemokine signaling pathway, Jak-STAT signaling pathway, Primary immunodeficiency

Chemokine signaling pathway, Jak-STAT signaling pathway, Primary immunodeficiency

WB 1:500

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Protein Kinase

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

JAK3

https://www.ncbi.nlm.nih.gov/gene/?term=3718

https://www.uniprot.org/uniprot/P52333