JAM3 Antilichaam

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.

83700

Q9BX67

Human

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human JAM3 (NP_116190.3) .

Unconjugated

Primary Antibodies

Cell Cycle, Immunology, Signal Transduction

Affinity purification

293T

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 37kDa

IgG

WB: 1:500 - 1:2000

JAM3

HeLa

Junctional adhesion molecule 3

Homo sapiens

JAM3, FLJ14529, JAM-C, JAMC, JAM-2, JAM-3

WB

Liquid