JE (MCP-1, CCL2)
Gecertificeerd

JE (MCP-1, CCL2)

Catalog #: M10-026-L100
Maat: 100 µg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Technische Specificaties

Description

The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant murine JE is a 13.8 kDa protein containing 125 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Synonyms

Ccl2; JE; HC11; MCAF; MCP1; MCP-1; Scya2; Sigje; SMC-CF; AI323594

NCBI Gene ID

20296

UniProt

P10148

Accession Number

NP_035463.1

Accession Number mRNA

NM_011333.3

Chromosomal Location

11 C-E1; 11 46.5 cM

Reactivity

Mouse

Cross Reactivity

Human, Mouse, Rabbit, Monkey, Bacteria

Sequence

QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

> 98% by SDS-PAGE & HPLC analyses

Bioactivity

Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 1.0-20.0 ng/ml.

Length

125

Form

Lyophilized

Molecular Weight

13.8 kDa

Host or Source

E. coli

Beschrijving

The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract

Specificaties

ProductnaamJE (MCP-1, CCL2)
Categorie
Beschikbare grootte100 µg
CatalogusnummerM10-026-L100