JMJD3 Antilichaam - middengebied: Biotine (ARP40102 T100-Biotine)

Lysine (K) -specific demethylase 6B

JMJD3, NEDCFSA

23135

O15054

AAH09994

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human JMJD3

JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.

WDR5; ASH2L; RBBP5; UBC; TK1; CSNK2B; HIST1H3A; WAS; SMAD3; SMAD2; SMAD4; SMAD1

Biotin

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

177kDa

Wet Ice

1643

KDM6B

KDM6B

Rabbit

Lysine-specific demethylase 6B

NM_001080424

AGLQGVVVLEQYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGS