JNJ-77242113 (Icotrokinra)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2763602-16-8
JNJ-77242113, JNJ-2113, PN-235
C06936-1mg
Interleukins
Immunology & Inflammation
C90H120N20O22S2
Icotrokinra (JNJ-77242113, JNJ-2113, PN-235) is an orally available and selective antagonist of the IL-23 receptor. It also inhibits IL-23–induced STAT3 phosphorylation in peripheral blood mononuclear cells with an IC50 of 5.6 pM and suppresses IL-23–induced IFN-γ production in NK cells with an IC50 of 18.4 pM. It also exhibits anti-inflammatory activity in a TNBS-induced colitis model in rats and holds potential for studying psoriasis, psoriatic arthritis, and inflammatory bowel disease.
Beschrijving
JNJ-77242113 (Icotrokinra) Beschikbaar in 1 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
BioCoupler® x 12
BC12
12 Each
Recombinant Common timothy PHLPIV/Phl p 4 Protein, N-His
YZZ03001
100 μg
NP (4-hydroxy-3-nitrophenylacetate)
NP-BSA-03Low – 10 mg
10 mg
NP (4-hydroxy-3-nitrophenylacetate)
NP-BSA-03High – 10 mg
10 mg
ExactaCruz® Pipette Tip Reload System, 50-1250 μl, case
sc-201714
80 Racks/Case
Disc Membrane Hydrophobic PTFE, 0.22μm
CPTB14222
50 PCS
Rat Serum Albumin
CSB-NP000101r-01
1 mg
Denhardt's Solution (50X)
EC-915
50 mL
