JST-TfR09
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
TXB4 (PPMX-T003) is a human monoclonal antibody (mAb) targeting CD71. JST-TfR09 can induce ferroptosis by reducing ferritin levels in ATLL cell lines, increasing the generation of ferrous iron and reactive oxygen species (ROS), and inducing lipid peroxidation via malondialdehyde. JST-TfR09 can be used in leukemia research. Recommended isotype control: Human IgG1 kappa, Isotype Control.
PPMX-T003
12352203
Ferroptosis; Reactive Oxygen Species (ROS) ; Transferrin Receptor
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Cancer-programmed cell death
Cancer
[JST-TfR09]
[1]Fauzi YR, et al. Anti-transferrin receptor antibody (JST-TFR09/PPMX-T003) induces ferroptosis in adult T-cell leukemia/lymphoma (ATLL) cells. Biochem Biophys Res Commun. 2025 Apr 5;756:151564.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991381/
Inhibitory Antibodies
No Development Reported
Beschrijving
TXB4 (PPMX-T003) is a human monoclonal antibody (mAb) targeting CD71. JST-TfR09 can induce ferroptosis by reducing ferritin levels in ATLL cell lines, increasin
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