K2C78 Antilichaam

This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified.

196374

Q8N1N4

Q8N1N4

Human

This K2C78 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-203 amino acids from the Central region of human K2C78.

Unconjugated

Primary Antibodies

Signal Transduction

This antibody is purified through a protein A column, followed by peptide affinity purification.

Batch dependent

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

57 kDa

Rabbit Ig

KRT78

Keratin, type II cytoskeletal 78

Homo sapiens

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007)

Schweizer, J., et al. J. Cell Biol. 174 (2) :169-174 (2006)

Rogers, M.A., et al. J. Invest. Dermatol. 124 (3) :536-544 (2005)

Hesse, M., et al. Eur. J. Cell Biol. 83 (1) :19-26 (2004)

Keratin, type II cytoskeletal 78, Cytokeratin-78, CK-78, Keratin-5b, Keratin-78, K78, Type-II keratin Kb40, KRT78, K5B, KB40

WB, Flow

166218809

Liquid