Kank3 Antilichaam

KANK3 Antibody: Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. Like other members of the KANK family, KANK3 (KN motif and ankyrin repeat domain-containing protein 3), is thought to play a role in the formation of actin stress fibers. In zebrafish, the homolog of KANK3 interacts with the adaptor protein Numb, a protein implicated in multiple basic cellular processes, and is essential for epidermal integrity and neurulation, suggesting that KANK3 may play a similar role in higher organisms.

256949

Q6NY19

NP_940873

Human, Mouse

Unconjugated

Primary Antibodies

Cancer, Cell Cycle

KANK3 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1202 - A431 Cell Lysate

1 mg/mL

KANK3 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

KANK3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

Two alternatively spliced transcript variants encoding different isoforms have been identified.

KANK3

Cat. No. 10-401 - Human Kidney Tissue Slide

KN motif and ankyrin repeat domains 3

Homo sapiens

Zhu Y, Kakinuma N, Wang Y, et al. Kank proteins: a new family of ankyrin-repeat domain containing proteins. Biochim. Biophys. Acta 2008; 1780:128-33.

Roy BC, Kakinuma N, Kiyama R. Kank attenuates actin remodeling by preventing interaction between IRSp53 and Rac1. J. Cell Biol. 2009; 184:253-67.

Boggetti B, Jasik J, Takamiya M, et al. NBP, a zebrafish homolog of human Kank3, is a novel Numb interactor essential for epidermal integrity and neurulation. Dev. Biol. 2012; 365:164-74.

KANK3 Antibody: ANKRD47, ANKRD47, KN motif and ankyrin repeat domain-containing protein 3, Ankyrin repeat domain-containing protein 47

ELISA, WB, IHC-P

157504499

Liquid