KCNA10 Antilichaam - middengebied: FITC (ARP35178_T100-FITC)

Potassium voltage-gated channel, shaker-related subfamily, member 10

Kcn1, Kv1.8

3744

Q16322

NP_005540

Human, Mouse, Rat, Cow, Dog, Guinea Pig

The immunogen is a synthetic peptide directed towards the middle region of human KCNA10

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Four sequence-related potassium channel genes, shaker, shaw, shab, and shal, have been identified in Drosophila, and each has been shown to have human homolog (s) . KCNA10 encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP.

POMP

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

IHC, WB

0.5 mg/ml

Cow: 100%; Dog: 92%; Guinea Pig: 92%; Human: 100%; Mouse: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

56kDa

Yao, X., et al., (2002) J. Am. Soc. Nephrol. 13 (12), 2831-2839

Wet Ice

511

KCNA10

KCNA10

Rabbit

Potassium voltage-gated channel subfamily A member 10

NM_005549

PANVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFW