KCNA5 Antilichaam - N-terminaal gebied: Biotine (ARP33977 P050-Biotin)

Potassium voltage-gated channel, shaker-related subfamily, member 5

HK2, HCK1, PCN1, ATFB7, HPCN1, KV1.5

3741

P22460

NP_002225

Human, Mouse, Rat

The immunogen is a synthetic peptide directed towards the N terminal region of human KCNA5

Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s) . KCNA5 encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion.

SIRT1; KCNAB2; ERBB2IP; SNTA1; HSP90AA1; TNK2; Rab11a; DCTN2; GNB2L1; KCNAB1; TFRC; SRC; PRKCQ; PRKCB; KCNA5; KCNA4; KCNA3; KCNA2; FYN; FHL1; DYNC1I1; CAV1; ACTN2; UBE2I; SUMO3; RAB5A; RAB4A; DLG4; DLG1; PTPRE

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Human: 100%; Mouse: 93%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

67kDa

Wet Ice

613

KCNA5

KCNA5

Rabbit

Potassium voltage-gated channel subfamily A member 5

NM_002234

DPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQR