KCNAB1 Antilichaam

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s) . This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes distinct isoforms which are encoded by alternatively spliced transcript variants of this gene. Some of these isoforms are beta subunits, which form heteromultimeric complexes with alpha subunits and modulate the activity of the pore-forming alpha subunits.

7881

Q14722

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 282-401 of human KCNAB1 (NP_751891.1) .

Unconjugated

Primary Antibodies

Neuroscience

Affinity purification

U-251MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 45-50kDa

IgG

WB: 1:200 - 1:2000

KCNAB1

293T

Mouse brain

Mouse kidney

Mouse heart

Rat brain

Potassium voltage-gated channel, shaker-related subfamily, beta member 1

Homo sapiens

KCNAB1, hKvb3, AKR6A3, KCNA1B, Kvb1.3, hKvBeta3, KV-BETA-1

WB

Liquid