KCNE1 Polyklonale Antilichaam, PE-Cy7 Vervoeging

Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 5 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr) .

ISK; JLNS; LQT5; MinK; JLNS2; LQT2/5; Potassium voltage-gated channel subfamily E member 1; Delayed rectifier potassium channel subunit IsK; IKs producing slow voltage-gated potassium channel subunit beta Mink; Minimal potassium channel; KCNE1

3753

P15382

Cytoplasm, Helical

Human, Mouse, Rat, Dog

41-129/129

KCNE1

PE-Cy7

KLH conjugated synthetic peptide derived from human KCNE1

WB

Purified by Protein A.

488nm/780nm

1µg/µl

WB (WB=1:500-2000)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

3753