KCNH2 Antilichaam / ERG- 1

KCNH2, also known as HERG or KV11.1, encodes the pore-forming subunit of a rapidly activating-delayed rectifier potassium channel. It is mapped to 7q36.1. KCNH2 forms the major portion of one of the ion channel proteins (the 'rapid' delayed rectifier current (IKr) ) that conducts potassium (K+) ions out of the muscle cells of the heart (cardiac myocytes), and this current is critical in correctly timing the return to the resting state (repolarization) of the cell membrane during the cardiac action potential.

Western blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL

Q12809

Human

Amino acids R159-A223 from the human protein were used as the immunogen for the KCNH2 antibody.

WB, Direct ELISA

Affinity purified

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

This KCNH2 antibody is available for research use only.

Store the KCNH2 antibody at -20°C.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the KCNH2 antibody should be determined by the researcher.

Western blot testing of human 1) K562 and 2) U-2 OS cell lysate with KCNH2 antibody. Expected molecular weight: 127-155 kDa.