KCNH6 Antilichaam - middengebied: Biotine (ARP35481_P050-Biotine)

Potassium voltage-gated channel, subfamily H (eag-related), member 6

ERG2, ERG-2, HERG2, Kv11.2, hERG-2

81033

Q9H252-2

NP_775115

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human KCNH6

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNH6 encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.

Biotin

Polyclonal Antibody

WB

Affinity Purified

KCNH6 is strongly supported by BioGPS gene expression data to be expressed in NCI-H226

0.5 mg/ml

Cow: 93%; Dog: 85%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 86%; Rabbit: 93%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

100kDa

Gutman, G.A., (2005) Pharmacol. Rev. 57 (4), 473-508

Wet Ice

905

KCNH6

KCNH6

Rabbit

Potassium voltage-gated channel subfamily H member 6

NM_173092

PLASPLHPLEVQGLICGPCFSSLPEHLGSVPKQLDFQRHGSDPGFAGSWG