KCNJ4 Antilichaam - middengebied HRP (ARP35167_P050-HRP)

Potassium inwardly-rectifying channel, subfamily J, member 4

HIR, HRK1, IRK3, HIRK2, IRK-3, Kir2.3

3761

P48050

NP_004972

Human, Mouse, Rat, Dog, Guinea Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human KCNJ4

KCNJ4 is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have??een found for this gene. Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neuronsSeveral different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene.

SNTA1; LIN7B; GNGT2; DLG2; IL16; DLG4; DLG1; KCNJ2; CASK; PRKCD; LIN7C; LIN7A; DMD

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

KCNJ4 is supported by BioGPS gene expression data to be expressed in HEK293T

0.5 mg/ml

Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

49kDa

Ji, W., (2008) Nat. Genet. 40 (5), 592-599

Wet Ice

445

KCNJ4

KCNJ4

Rabbit

Inward rectifier potassium channel 4

NM_004981

AVAAGLGLEAGSKEEAGIIRMLEFGSHLDLERMQASLPLDNISYRRESAI