KCNMA1 Antilichaam - middengebied: Biotine (ARP37677_P050-Biotine)

Potassium large conductance calcium-activated channel, subfamily M, alpha member 1

SLO, BKTM, SLO1, hSlo, IEG16, LIWAS, MaxiK, PNKD3, SAKCA, mSLO1, CADEDS, KCa1.1, SLO-ALPHA, bA205K10.1

3778

Q12791

NP_001014797

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human KCNMA1

This protein is a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm.MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.

EED; TBXA2R; KCNMB1; KCNMA1; CAV3; CAV2; CAV1; ACTG2; ACTA2; ALB; CACNA1H; PTK2; MAP1A; GGT1; HMOX2

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 85%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

131kDa

Cambien, B., (2008) Int. J. Cancer 123 (2), 365-371

Wet Ice

1182

KCNMA1

KCNMA1

Rabbit

Calcium-activated potassium channel subunit alpha-1

NM_001014797

ESRSRKRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITD

Alpha-1