KCNMB3 Antilichaam - middengebied: Biotine (ARP35444 P050-Biotine)

Potassium large conductance calcium-activated channel, subfamily M beta member 3

HBETA3, KCNMB2, KCNMBL, BKBETA3, SLOBETA3, SLO-BETA-3, K (VCA) BETA-3

27094

Q9NPA1-2

NP_741979

Human, Rat, Dog

The immunogen is a synthetic peptide directed towards the middle region of human KCNMB3

KCNMB3 is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. At least four transcript variants encoding four different isoforms have been found for KCNMB3.MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. At least four transcript variants encoding four different isoforms have been found for this gene.

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Dog: 91%; Human: 100%; Rat: 92%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

31kDa

Lorenz, S., (2007) Am. J. Med. Genet. B Neuropsychiatr. Genet. 144 (1), 10-13

Wet Ice

277

KCNMB3

KCNMB3

Rabbit

Calcium-activated potassium channel subunit beta-3

NM_171828

SLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQFKLC

Beta-3