KCNN4 Antilichaam / KCa3.1 / SKCa4

Intermediate conductance calcium-activated potassium channel protein 1 (KCNN4, Kca3.1) is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. KCNN4 may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.

Western blot: 0.5-1 µg/mL

O15554

Human, Mouse, Rat

An amino acid sequence from the N-terminus of human KCNN4 (RRKRLLEQEKSLAGWA) was used as the immunogen for this KCNN4 antibody.

WB

Antigen affinity

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This KCNN4 antibody is available for research use only.

After reconstitution, the KCNN4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

The stated application concentrations are suggested starting amounts. Titration of the KCNN4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Western blot testing of 1) human placenta, 2) rat brain and 3) mouse brain tissue lysate with KCNN4 antibody. Predicted molecular weight ~48 kDa.