KCNT2 (NM 198503) Human Recombinant Proteïne

Outward rectifying potassium channel. Produces rapidly activating outward rectifier K (+) currents. Activated by high intracellular sodium and chloride levels (PubMed:14684870, PubMed:16687497, PubMed:29069600) . Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane (PubMed:16687497) (By similarity) . Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRM1 (PubMed:16687497) .[UniProtKB/Swiss-Prot Function]

Purified recombinant protein of Human potassium channel, subfamily T, member 2 (KCNT2), Gly957-Arg1012, with N-terminal His-ABP tag, expressed in E. coli, 50ug

EIEE57; KCa4.2; SLICK; SLO2.1

343450

Q6UVM3, A9LNM6

NM_198503

1q31.3

E. coli

N-His-ABP

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol.

Druggable Genome, Ion Channels: Potassium, Transmembrane

21.5 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

KCNT2

Human

NP_940905

https://www.ncbi.nlm.nih.gov/gene/343450

https://www.uniprot.org/uniprot/Q6UVM3

https://www.ncbi.nlm.nih.gov/nuccore/NM_198503

https://www.ncbi.nlm.nih.gov/nuccore/NP_940905