KCTD15 Antilichaam

KCTD15 Antibody: Childhood and adult obesity in the United States and to a lesser extent the rest of the world has increased dramatically over the past decade. Both environmental and genetic factors are involved in the onset and progression of weight gain. Recently, the potassium channel KCTD15 was identified as a genetic loci associated with higher than normal body mass index (BMI) in humans along with genes such as GNPDA2, MTCH2, FTO, and TMEM18. Further studies on single nucleotide polymorphisms (SNPs) in non-diabetic and diabetic patients showed that FTO was most strongly associated with obesity while MTCH2 and GNPDA2 were still significantly associated with higher than normal BMI levels. At least two isoforms of KCTD15 are known to exist.

79047

Q96SI1

Q96SI1

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Obesity

KCTD15 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1201 - HeLa Cell Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Bovine: (100%)

KCTD15 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

KCTD15 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

KCTD15

Cat. No. 10-901 - Human Spleen Tissue Slide

Potassium channel tetramerisation domain containing 15

Homo sapiens

Hill JO. Genetic and environmental contributions to obesity. Am. J. Clin. Nutr.1998; 68:991-2.

Willer CJ, Speliotes EK, Loos RJ, et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat. Genetics2009; 41:25-34.

Renstrom F, Payne F, Nordstrom A, et al. Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden. Human. Mol. Gen.2009; 18:1489-96.

KCTD15 Antibody: Potassium channel tetramerization domain-containing protein 15

ELISA, WB, IHC-P, IF

74732704

Liquid