Keratine 18 (Ab 33)

KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. utations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

3875

P05783

NP_000215.1

Human

Keratin 18 (Ab-33) antibody was raised against a peptide sequence around aa.31~35 (A-A-S-V-Y) derived from Human Keratin 18 (CK18) .

Unconjugated

Primary Antibodies

Other

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

46 kDa

This antibody detects endogenous level of total Keratin 18 protein.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

KRT18

Keratin 18

Homo sapiens

Ramaekers, F. C. and Bosman, F. T. (2004) J. Pathol. 204, 351-354. Chang, L. and Goldman, R. D. (2004) Nat. Rev. Mol. Cell Biol. 5, 601-613. Moll, R. et al. (1982) Cell 31, 11-24.

K18, CYK18, FAK, FAK1, CK 18, CK18, Cytokeratin endo B, K18

WB, IHC

4557888

Liquid