KHDRBS2 Antilichaam - N-terminalgebied: FITC (ARP53109_P050-FITC)

KH domain containing, RNA binding, signal transduction associated 2

SLM1, SLM-1

202559

Q5VWX1

NP_689901

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human KHDRBS2

KHDRBS2 is a RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. KHDRBS2 induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. KHDRBS2 may function as an adapter protein for Src kinases during mitosis. KHDRBS2 binds both poly (A) and poly (U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability.

HBZ; DOCK2; CIRBP; TYMSOS; LINC01018; KHDRBS2; ZFC3H1; CATSPER1; YTHDC1; PRR3; NABP1; AEN; NCOA5; NPDC1; RBMX; PRPF31; CHTOP; HNRNPR; MTA1; TYK2; SULT1A3; SPG7; SDCBP; RBM3; PTK6; UBC; KHDRBS3; HNRNPK; LYN; HNRNPC; HNRNPA2B1; HNRNPA1; FGG; FGB; FGA; DSG1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

39kDa

Wet Ice

349

KHDRBS2

KHDRBS2

Rabbit

KH domain-containing, RNA-binding, signal transduction-associated protein 2

NM_152688

EEIEKFQGSDGKKEDEEKKYLDVISNKNIKLSERVLIPVKQYPKFNFVGK