KHSRP Antilichaam - middelste regio: FITC (ARP40474 P050-FITC)

KH-type splicing regulatory protein

P75, FBP2, KSRP, FUBP2

8570

Q92945

NP_003676

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of Human KHSRP

KHSRP binds to the dendritic targeting element and may play a role in mRNA trafficking. It is part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. KHSRP mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. It may interact with single-stranded DNA from the far-upstream element (FUSE) .It is also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.

HUWE1; Bace1; UBC; STAU1; LGR4; MDM2; WWOX; SUZ12; EED; RNF2; NAP1L4; HNRNPD; GFPT1; GARS; APBB1; ALDH16A1; TARDBP; CD81; MPG; UBL4A; WHSC1; VCAM1; ITGA4; FN1; STRIP1; ASF1B; CPLX1; CIRBP; SUMO1; RAE1; CAND1; COPS5; CUL1; CUL2; CUL3; CUL4B; CUL5; NEDD8; C

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

IHC, WB

Affinity Purified

KHSRP is strongly supported by BioGPS gene expression data to be expressed in HEK293T

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

73kDa

Wet Ice

711

KHSRP

KHSRP

Rabbit

Far upstream element-binding protein 2

NM_003685

WEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGG