KIF7 Antilichaam

This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.

374654

Q2M1P5

Human

Recombinant fusion protein containing a sequence corresponding to amino acids 1044-1343 of human KIF7 (NP_940927.2) .

Unconjugated

Primary Antibodies

Cell Cycle, Signal Transduction, Stem Cell

Affinity purification

Jurkat

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 150kDa

IgG

WB: 1:200 - 1:2000

KIF7

LO2

A-549

Kinesin family member 7

Homo sapiens

ACLS, AGBK, HLS2, JBTS12, UNQ34kinesin-like protein KIF7, EQYK340

WB

Liquid