KIF7 Antilichaam - C-terminalgebied: Biotine (ARP62009 P050-Biotin)

Kinesin family member 7

ACLS, AGBK, HLS2, JBTS12, UNQ340

374654

Q2M1P5

NP_940927.2

Human, Mouse, Rat, Cow, Dog, Pig

The immunogen is a synthetic peptide directed towards the C-terminal region of human KIF7

This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 92%; Dog: 79%; Human: 100%; Mouse: 77%; Pig: 100%; Rat: 77%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

91kDa

Wet Ice

829

KIF7

KIF7

Rabbit

Kinesin-like protein KIF7

NM_198525.2

RDLVHAPLPLTWKRSSLCGEEQGSPEELRQREAAEPLVGRVLPVGEAGLP