KIT Antilichaam

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor) . Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

3815

P10721

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 25-295 of human KIT (NP_000213.1) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology, Neuroscience, Signal Transduction, Stem Cell

Affinity purification

A-549

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 120kDa/145kDa

IgG

KIT

Mouse brain

Mouse lung

Rat brain

KIT proto-oncogene receptor tyrosine kinase

Homo sapiens

Mast/stem cell growth factor receptor Kit, SCFR, Piebald trait protein, PBT, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, p145 c-kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, CD117, KIT, SCFR

WB, IHC, IF

Liquid