KL-001
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
A novel tool that specifically interacts with cryptochrome (CRY) preventing its ubiquitin-dependent degradation resulting in lengthening of the circadian period. KL-001-mediated CRY stabilization inhibits glucagon-induced gluconeogenesis in primary hepatocytes1. Binds to the FAD-binding pocket of CRY2 as determined by co-crystal structure2. Induces an increase in period along with simultaneous reduction in amplitude of circadian reporter expression3 in mammalian cells.
Unconjugated
White solid
RT
Beschrijving
KL-001 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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