KLF1, 2, 4 Polyklonale Antilichaam, PE-Cy5,5 Vervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Transcription regulator of erythrocyte development that probably serves as a general switch factor during erythropoiesis. Is a dual regulator of fetal-to-adult globin switching. Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene. Furthermore, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes. This dual activity ensures that, in most adults, fetal hemoglobin levels are low. Able to activate CD44 and AQP1 promoters. When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation (By similarity) .
EKLF; INLU; CDAN4; HBFQTL6; Krueppel-like factor 1; Erythroid krueppel-like transcription factor; KLF1
10661
Q13351
Nucleus
• Rabbit
Human, Mouse, Rat
265-362/362
KLF1, 2, 4
• Polyclonal
• IgG
PE-Cy5.5
KLH conjugated synthetic peptide derived from human KLF1
WB
Purified by Protein A.
488nm/694nm
1µg/µl
WB (1:300-5000)
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
10661
Beschrijving
KLF1, 2, 4 Polyklonale Antilichaam, PE-Cy5,5 Vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
Specificaties
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